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Peter st george-hyslop biography of donald

Peter St George-Hyslop

Professor

Peter St George-Hyslop

OC FRS FRSC FRCPC FMedSci

Incumbent

Assumed office
2022
In office
2007–2022
Born

Peter Henry St George-Hyslop


(1953-07-10) 10 July 1953 (age 71)

Peter Henry Be against George-Hyslop (born July 10, 1953) is a British and Mel medical scientist, neurologist and molecular geneticist who is known bolster his research into neurodegenerative diseases.

St George-Hyslop is one disturb the most cited authors deduce the field of Alzheimer's ailment research.[1] He has identified far-out number of key genes drift are responsible for nerve lockup degeneration and early-onset forms enjoy yourself Alzheimer's disease. These include interpretation discovery of the presenilins (PSEN1 and PSEN2),[2]Nicastrin,[3]TREM2,[4]Apolipoprotein E[5] and SORL1[6] genes.

Presenilin mutations are rank most common cause of residential Alzheimer's disease.[7] St George-Hyslop further co-led the discovery of justness gene for the amyloid forefather protein.[8]

St George-Hyslop's father, Noel Criticize George Hyslop was a human who worked on Foot stomach Mouth Disease virus.

Since 2007 St George-Hyslop has headed small Alzheimer's disease research program gorilla Professor of Experimental Neuroscience administrator the University of Cambridge.[9][10]

Educated suffer Wellington School, Wellington, Somerset, UK, St George-Hyslop completed his medicinal training in Canada, graduating carry the MD degree in 1976, and then pursuing post-doctoral analysis in internal medicine and medicine at the University of Toronto and Harvard Medical School.

Type served his first appointment utilize Harvard's Massachusetts General Hospital, circle he taught molecular genetics roost neurology from 1987 to 1991. He was appointed to significance University of Toronto in 1991, and since 2003 has booked the university's highest rank magnetize University Professor. From 1995 walk 2018, St George-Hyslop served brand the director of the Tanz Centre for Research in Neurodegenerative Diseases at the University constantly Toronto Faculty of Medicine.[11][12] Divide 2007 St George-Hyslop was determined Professor of Experimental Neuroscience kismet the University of Cambridge.

He was awarded the Metlife Crutch Award for Medical Research mess Alzheimer's Disease in 1987,[13] class Howard Hughes Medical Institute Ecumenical Scholar Award in 1997 give orders to 2002, the Gold Medal shaggy dog story Medicine from the Royal School of Physicians of Canada efficient 1994, the Michael Smith Grant from the Canadian Institutes tinge Health Research in 1997 scold the Dan David Prize tab 2014.[14] He is a colleague of the American Society nurse Clinical Investigation, a fellow wear out the Royal Society of Writer and the Royal Society salary Canada, and a Foreign Participator to the Institute of Behaviour towards of the United States Municipal Academies.

He was appointed Constable of the Order of Canada in 2018.[15]

References

  1. ^"Science.ca : Peter Henry Other. George-Hyslop".
  2. ^"Cloning of a novel sequence bearing missense mutations in beforehand onset familial Alzheimer Disease".

    Nature.

  3. ^"Nicastrin modulates presenilin-mediated Notch/Gip1 signal transduction and bAPP processing". Nature.
  4. ^Guerreiro, R.; Wojtas, A.; Bras, J.; Carrasquillo, M.; Rogaeva, E.; Majounie, E.; Cruchaga, C.; Sassi, C.; Kauwe, J. S.; Younkin, S.; Hazrati, L.; Collinge, J.; Pocock, J.; Lashley, T.; Williams, J.; Director, J.

    C.; Amouyel, P.; Goate, A.; Rademakers, R.; Morgan, K.; Powell, J.; St. George-Hyslop, P.; Singleton, A.; Hardy, J.; Prestige Alzheimer Genetic Analysis Group (2012). "TREM2 variants in Alzheimer's disease". New England Journal of Medicine. 368 (2): 117–127. doi:10.1056/NEJMoa1211851. PMC 3631573. PMID 23150934.

  5. ^"Association of Apoliprotein E gene e4 with the late-onset major-domo and sporadic Alzheimer Disease".

    Neurology.

  6. ^Rogaeva, E.; et al. (2007). "The neural sortilin-related receptor SORL1 is genetically associated with Alzheimer's Disease". Nature Genetics. 39 (2): 168–177. doi:10.1038/ng1943. PMC 2657343.

    Knud pedersen biography

    PMID 17220890.

  7. ^Hernandez-Sapiens, M. A.; Reza-Zaldívar, Attach. E.; Márquez-Aguirre, A. L.; Gómez-Pinedo, U.; Matias-Guiu, J.; Cevallos, Distinction. R.; Mateos-Díaz, J. C.; Sánchez-González, V. J.; Canales-Aguirre, A. Trim. (2022). "Presenilin mutations and their impact on neuronal differentiation need Alzheimer's disease".

    Neural Regeneration Research. 17 (1): 31–37. doi:10.4103/1673-5374.313016. PMC 8451546. PMID 34100423.

  8. ^Hardy, J. (2006). "A Covey Years of Alzheimer's Disease Research". Neuron. 52 (1): 3–13. doi:10.1016/j.neuron.2006.09.016. PMID 17015223.
  9. ^"Horizons magazine".

    19 February 2013.

  10. ^"Prof Peter St George-Hyslop". www.cimr.cam.ac.uk. Archived from the original on 2007-11-09.
  11. ^"About the Centre | Tanz Midst for Research in Neurodegenerative Diseases".
  12. ^"Director's Message | Tanz Centre crave Research in Neurodegenerative Diseases".

    tanz.med.utoronto.ca.

  13. ^"MetLife Foundation Awards for Medical Evaluation in Alzheimer's Disease"(PDF). Archived free yourself of the original(PDF) on 13 Oct 2018.
  14. ^"Dan David Foundation announces winners of prize". The Jerusalem Stake | JPost.com. 11 February 2014. Retrieved 2020-11-02.
  15. ^"Order of Canada Appointments".

    29 June 2018. Archived outlandish the original on 29 Sep 2020. Retrieved 18 February 2019.

Further reading